Y.I. Bandazheusky. Processes of Antenatal and Postnatal Development of Syrian Hamsters  Under Conditions of a  Radiation-Chemical Factor as  Part of  a Food Product  – Oat Grain Grown within the   Area Affected by the Accident at the Chernobyl Nuclear Power Plant  [Text] /Y.I. Bandazheusky, N.F. Dubova, V.V. Schwartau, I.P. Kozyarin //Collection of Research Papers by Colleagues of the National Medical Academy of Postgraduate Education named after P.L.Shupyk. – Кiev, 2013. – P. 110-118.with abstract ( Download ZIP^[scan])

Y.I. Bandazhevsky, N.F. Dubova, V.V. Schwartau, I.P. Kozyarin

Processes of Antenatal and Postnatal Development in Syrian Hamsters Under Conditions of a Radiation-Chemical Factor as Part of a Food Product - Oat Grain Grown within the Area Affected by the Accident at the Chernobyl Nuclear Power Plant

Introduction. After 25 years since the accident at the Chernobyl nuclear power plant, there is an open question on whether it is possible to receive farm products safe for human health within the affected area. In this respect, it is advisable to conduct experimental studies involving laboratory animals with further extrapolation of received results to humans.

Purpose. A study of processes of prenatal and postnatal development in the laboratory animals - Syrian hamsters (Mesocricetus auratus) - under the influence of a radiation-chemical factor as part of a food product - oat grain grown within the area affected by the accident at the Chernobyl nuclear power plant.

Methods. Physiological, morphological (embryological), haematological, biochemical, radiometric, physico-chemical, mathematical-statistical.

Results. Found that the grain oats, grown in 2011, in the areas affected by the Chernobyl nuclear power plant, has, in comparison with the control, increased amounts of radionuclides Cs-137 and Sr-90, as well as the chemical elements Ba, Sr, Mn (in 2,0 or more time). Identified significant violations of the processes of antenatal and postnatal development of offspring of Syrian hamsters, who ate grains indicated in pregnancy and lactation. Interruption of pregnancy in the pre-implantation stage stated in 43.3 % of all cases of fertilization (in the control group - in 23.8% of cases). In 41.2 % of pregnancies registered fetuses with birth defects, in the form of cleft lip and palate, cerebral hernia, exencephaly (in the control group - 12.5 % of pregnancies (p <0,05)). A statistically significant decrease in the number of red blood cells, decrease in hemoglobin, the rise in the number of eosinophils and high content of urea in the blood serum of calves main group compared to the control, indicating that the occurrence of structural and functional changes in the vital organs of test animals.

Summary. The received results pay attention to the necessity to evaluate the role of the radiation-chemical factor present in soils of areas affected by the accident at the Chernobyl nuclear power plant in the reproductive losses in humans.

Кey words: radiation-chemical factor, Syrian hamsters, prenatal development, postnatal development, radioactive contaminated areas, accident at the Chernobyl nuclear power plant.